Telomeres and Tumors Paper Research Example | Topics and Well Written Essays - 2000 words

Telomeres and Tumors - Research Paper Example At once, the DNA at the finishes of chromosomes appeared to be static. However in many creatures that have been contemplated, the tips, called telomeres, are entirely transforming; they abbreviate and extend repeatedly† (Glieder and Blackburn). Since the previous fifteen years, there have been amazing discoveries, concerning this change. Getting to the particulars, it has prompted the revelation of theastonishing protein, telomerase that follows up on telomeres and is viewed as a pre imperative for the upkeep of malignant growth in individual. Geneticists, Barbara McClintock, of University of Missouri at Columbia, and Hermann J. Muller, from the University of Edinburgh, are credited with having accomplished broad work on the complicated subjects of telomeres and telomerase. These researchers workedunconnectedly and with disparate creatures, anyway them two understood that chromosomes were balanced out by an uncommon part on their closures. â€Å"Muller authored the term telome re, from the Greek for end (telos) and part (meros). McClintock noticed that without these end tops, chromosomes stick to each other, experience basic changes and get rowdy in different manners. These exercises undermine the endurance and loyal replication of chromosomes and, thus, of the cells lodging them.† (Glieder and Blackburn). ... â€Å"The watched heterogeneity drove Blackburn, who had moved to the University of California at Berkeley, Jack W. Szostak of Harvard University and Janis Shampay of Berkeley to propose another answer for what has been known as the end-replication problem† (Glieder and Blackburn). â€Å"In 1972 James D. Watson, working at both Harvard and Cold Spring Harbor Laboratory, noticed that DNA polymerases, the compounds that recreate DNA, couldn't duplicate direct chromosomes right to the tip. Thus, the replication hardware needed to leave a little area toward the end (a bit of the telomere) un-copied.† (Glieder and Blackburn). Hypothetically, if the phones couldn't repay for this accident, chromosomes would diminish in their separate lengths, with each degree of mitosis. The erosion from now on annihilating the telomeres and dangerous qualities in some gathering of the phones. The varieties in the length of telomere, for the researchers, were a marker that cells maintain telo meres at a steady size, or possibly they attempt to. The telomeres decline long during mitosis, however their length likewise increments as newly shaped subunits append themselves to them. â€Å"The specialists associated that the source with these extra rehashes was some unfamiliar compound fit for a stunt that standard DNA polymerases couldn't perform.† (Glieder and Blackburn). â€Å"When cells reproduce their chromosomes, which comprise of two strands of DNA contorted around one another, they start by isolating the twofold helix. The polymerases utilize each of these parentstrands as a layout for building another accomplice. The extraordinary compound the laborers imagined would have the option to construct expansions to single strands of DNA without any preparation, without advantage of a current DNA template.† (Glieder

Arthur Miller Essay

Somewhere in the range of 1949 and 1953, Arthur Miller composed two of his most well known plays. The two plays managed serious issues in the public eye. The primary characters of the plays were comparable. Additionally, the supporting characters of the two plays were indistinguishable. Arthur Miller’s plays Death of a Salesman and The Crucible are comparable from numerous points of view. The principle reason for both Death of a Salesman and The Crucible was to show serious issues in American culture. In Death of a Salesman, Arthur Miller was attempting to show the inconceivabilities of the American Dream. In The Crucible, he was attempting to show how society is bigoted toward others and is inclined to delirium. The two plays managed society vanquishing the normal, dedicated man. Each play demonstrated a general public that was loaded with double dealing and liars. In both of these plays, society was portrayed as a malicious thing that would overwhelm the normal individual an d make an unjustifiable world. The principle characters of Death of a Salesman and The Crucible, Willy Loman and John Proctor, were indistinguishable from numerous points of view. Both of these men had extramarital illicit relationships, and in the two cases, the issues wound up annihilating their lives. Both of these men were persevering, normal men who were simply attempting to make a decent life for themselves and their families. Names were critical to the two men, and the two of them invested wholeheartedly in their names. In the two cases, numerous choices the two made were a direct result of their relatives. One huge likeness among Willy and John was the way that the two of them in the long run passed on, and the demise was mostly their decision. The two men could have stayed away from death, however rather, they decided to pass on in light of the fact that they trusted it was the right activity. In these two plays, there were likewise numerous similitudes between the supporting characters. In the two plays, kids had significantly more force than they ordinarily do. In Death of a Salesman, Willy’s child controlled quite a bit of his life. In The Crucible, the young ladies, drove basically by Abigail Williams, made numerous individuals be hanged, and considerably more to be detained. Likewise, both John and Willy had spouses that were faithful to them for the duration of their lives and upheld them until the end. The two plays demonstrated a figure of intensity, seen as Howard in one play and Judge Danforth in the other. In the two plays, the primary character had a companion who defended them toward the end. Willy had Charley, who had been his closest companion for quite a while, and John had Reverend Hale, who attempted to forestall John’s demise. There are numerous likenesses between characters in the two plays. Demise of a Salesman and The Crucible are similar from multiple points of view. Arthur Miller made comparative characters in the two plays. He utilized both to show the numerous things wrong in America. These two plays are both incredible bits of writing that ought to be perused and increased in value by all people.Sources: Death of a Salesman and The Crucible by Arthur Miller Arthur Miller Essay Can the crowd be sure that Abigail is imagining when she has her fits (pages thirty nine-forty and ninety one-ninety six) In sixteen ninety two there was a flare-up of hangings for black magic. Arthur Miller put together â€Å"The Crucible† with respect to the occasions that lead to this to make a moral story of the occasions that occurred in the nineteen fifties, when Joseph McCarthy was the leader of the examinations of the senate advisory group on inward security. When Abigail her fit on page ninety two, Miller leaves the crowd confounded in light of the other girls’ response to what Abigail does and furthermore to Mary Warren’s allegations. When Abigail begins emulating Mary Warren the young ladies duplicate Abigail and begin utilizing it to blame Mary Warren for â€Å"sending a shadow on them,† so Abigail utilized its abrupt passage into the court to prevent Mary Warren from coming clean about what occurred in the forested areas. The manner in which they decided to denounce her was by copying Mary Warren. â€Å"Mary Warren (shouting out as loud as possible, and raising her clench hands): Stop it!! Young ladies (raising their clench hands): Stop it!! † Arthur Miller includes more vulnerability by making different young ladies driving into the fits. This happens when Betty wakes upon page thirty nine and starts a fit off by saying, â€Å"I saw Goody Howe with the Devil! † This is compelling on the grounds that Betty is obviously sick at the time this happens then â€Å"As she is speaking BETTY is ascending from the bed, a fever in her eyes, and gets the serenade. † Then in a fit on page ninety two, Mercy Lewis says â€Å"Mercy Lewis (pointing): It’s on the pillar! Behind the beam! † This is the point at which the winged animal has showed up and Danforth asks where it was. This is a viable procedure to utilize and these focuses in the play since it keeps the crowd speculating and needing to realize what will occur straightaway. Mary Warren is available during both the fits that Abigail has, in spite of the fact that in the subsequent one on page ninety two she is the one both blaming and being charged. Toward the finish of the fit Mary Warren has a genuine pressure actuated fit â€Å"only MARY is left there, gazing up at the 'bird’, shouting frantically. All watch her startled by this clear fit. † The way that Mary Warren has now joined in isn’t the main thing that makes this powerful it is that she has quite recently altered her perspective in the wake of being so undaunted on coming clean, likewise this involves Proctor similar to a witch since he is the one that took her to the court. In the sixteen nineties the structures were outfitted in a moderate manner since individuals couldn’t bear the cost of substantially more that the basics, for instance in Betty’s room would have a bed a little bureau for her garments and a seat. There would likewise be a couple of windows. Along these lines it would be very stunning seeing it topped off with for the most part little youngsters, at that point when all the young ladies unexpectedly begin yelling it would be overpowering and very confounding for a group of people part observing this just because. Nonetheless, When Mary Warren is convinced to go to court she appears to be terrified of Abigail as she says; â€Å"She’ll murder me for sayin’ that! † The crowd additionally realize that Abigail has lied from the earliest starting point about what occurred in the forested areas, as Abigail disclosed to her uncle that everything they did was move yet then Betty says â€Å"you drank an appeal to slaughter Goody Proctor! Additionally in a similar discussion Abigail reveals to Mary Warren to continue lying, â€Å"Let both of you hint even the slightest bit at different things and I will come to you operating at a profit of some horrendous night and I will bring pointy figuring that will shiver you. † When the young ladies duplicate Abigail they never get on straight away they generally require a significant stretch of time to participate, for example, in the court on page ninety two Abigail needs to rehash what Mary Warren says twice before the young ladies begin rehashing also. â€Å"The Crucible† is a purposeful anecdote of what was going on in America in the nineteen fifties. At the point when Joseph McCarthy turned into a representative bunches of individuals began experiencing difficulty with being blamed for being a socialist. It was essentially entertainers, on-screen characters and journalists that were charged yet once you were denounced there were just two things you could do to prevent yourself from being boycotted, which implied you would think that its difficult to work once more, you could either confess to being a socialist and still be boycotted or you could do the simpler thing to demonstrate you weren’t a socialist which was blame another person. This is fundamentally the same as â€Å"The Crucible† as Abigail feels she needs to denounce Tituba with the goal that she isn’t blamed for which make. The main two contrasts when you were placed in this circumstance product that you wouldn’t be hung for being a socialist you just wouldn’t have the option to look for some kind of employment without any problem. The other contrast was that in Salem you must be a witch to be hung, though in America you must be a socialist. There are sure likenesses among Salem and today, for example, today, loads of individuals treat Muslims diversely in light of the fact that others have transformed Muslims into a substitute and anticipated everything amiss with the general public that they live in and been accused on a specific gathering of individuals, which for our situation is Muslims. This bias against specific gatherings of individuals regularly isn’t reasonable. In America they anticipated their feelings of dread onto socialists since they were that the socialist uprising in Russia would spread to America, however now we are concerned on the grounds that a couple of Muslims out of millions chose to become self destruction aircraft and the legislature utilized them as a way to legitimize the war in Iraq by vilifying the fundamental confidence in that nation. In general I believe that the crowd wouldn’t have the option to whether Abigail was imagining while she was having her fits except if they had seen â€Å"The Crucible† previously, in light of the fact that Arthur Miller utilizes a great deal of strategies to befuddle or alarm the crowd.

The Debate Over Social Security Today Research Paper

The Debate Over Social Security Today - Research Paper Example The program made to help the individuals who are jobless in US is as yet practical and the program that was made to help the families that have dependant kids has been changed into a program made to help the poor ones. The time of the Great Depression prompted the formation of Social Security Act yet a similar thought existed even before this timeframe. For instance: during the 1880s a program to help the old matured individuals, pregnant ladies and sick individuals was useful in Germany. These projects are supposed to be created because of the urbanization of Germany. Thus, the program of social protection is said to have created because of the urbanization in US. During the time of 1880s the quantity of individuals working in ventures and number of individuals working in ranches and horticultural field were equivalent. By the 1930s, the quantity of individuals working in ranches diminished to 21% of the absolute workforce and individuals began picking up wage based work in the mode rn part. Further expresses that the wages earned by individuals working in industrialized territories were variable in nature even before the Great Depression. Prior to the Great Depression, the joblessness rate between the periods of 1905 to 109 varied from as low as 3.9% to 16.4% and the joblessness rate during the time of 1920 to 1924 vacillated from 4.1% to 19.5% (Kennedy, 1999). At whatever point monetary downtrend occurred in US, the classification of individuals who took the greater part of the weight were the old matured individuals, opposite symptoms of downtrend included loss of pay because of weaknesses and passing. These impacts picked up the consideration of the approach creators and during the Great Depression these issues increased more quality as during this period the joblessness rate in non agrarian segments raised to 34%. Increment in the level of these issues caused the arrangement creators to make the Social security program (Green, 2003). The early evolved prog ram of Social Security was not structured in a manner to give quick help from the impacts of the Great sadness. The early program was to some degree like the Townsend plan as per which people maturing 60 or more were given a mature age benefits of $200. This sum was just given to those people who were not utilized or couldn't work and they needed to spend the whole sum in one specific months timeframe. This program never turned into a piece of the US constitution however increased gigantic prevalence since it concentrated on cleaning of neediness and to acquire monetary achievement. Body Several highlights of the Social Security Act of 1935 are as yet accessible in the present Social security framework, throughout the years the framework has encountered different changes. The progressions made to the demonstration during the period of 1939 have now become a piece of discussion. The Act in its actual shape was made to give retirement assets to the individuals who were not, at this po int utilized and were maturing more than 65 years. The detailing of the advantages that should have been offered to old matured individuals under this demonstration depended on the salary earned by these old matured individuals since 1937 and the advantages were offered to individuals originating from restricted sorts of occupations. The primary detailing of advantages offered extremely low advantages to the old matured individuals when contrasted with the wages earned by a normal laborer during that timespan (Livingston, 2008). These advantages were never applied to the Social Security Act; the main highlights applied from this Social Security A

Analysis of an Angel Island poem Essay Example | Topics and Well Written Essays - 500 words

Examination of an Angel Island sonnet - Essay Example It is clear the carvings and compositions are remaining proof showing the encounters of Chinese outsiders and events at Angel station in San Francisco. The sonnets found at the station are the most sensational disclosures in American writing. Today, in any event researchers are deciphering and deciphering sonnets over the world (Lai, Lim, and Yung 12). Cut on wooden structures by Chinese settlers who never became workers in America following Exclusion Act, the sonnets uncover the uncommon detainment of foreigners for quite a long time and months on the island anticipating freedom by American movement authorities (Lai, Lim, and Yung 20). Furthermore, these sonnets uncovered the work conditions and financial conditions in California in the twentieth century. By giving a point by point record of the situation of Chinese outsiders in San Francisco, the assortment of sonnets addressed American belief systems of boundless and equivalent open door coasted in the twentieth century. It is obvious the sonnets uncover different subjects not restricted to movement, distance, race, and work in America. A migrant from Heungshan composed a noticea ble sonnet that melds the encounters and events in San Francisco to show a few subjects. The sonnet was converted into English by Lai, Lim and Yung (1991) and composed into exposition. As indicated by the sonnet, Angel Island Immigration Station was a position of affliction and bitterness. The Chinese settlers were looking for work openings so as to gain a living in America. The Exclusion Act in late twentieth century that denied expanded Chinese relocation prompted sufferings and issues. Numerous foreigners remained in unhygienic and unfortunate conditions anticipating leeway from movement authorities, and the carvings and compositions exhibit the sharpness and hatred among outsiders. In any case, numerous Chinese workers suffered and withstood conditions at Angel Island Immigration

The Pain And Suffering Of The Voiceless People In Cinema Essay

The Pain And Suffering Of The Voiceless People In Cinema - Essay Example The need of depending on non-verbal correspondence is to be sure evident in the film, for the conspicuous explanation that the apparent casualties in the film are voiceless and weak. Without words, what is left for them is non-verbal communication, through move joined by music. The meaning of move as a type of articulation that utilizes materially developments that are musical, designed, now and then extemporized, found in each culture and is performed for purposes going from the stately, ritualistic and supernatural to the showy, social and basically feel (Britannica 2011), moderately associates with the film. The music that was without words and the moves were very engaging in the film. The developments were expressive, which was illustrative of the reflex reaction of the kids when at serious risk, which is to either escape or given up to conceal the dread. The movement is on the side of the craving of the caught youngsters to promptly take care of the negative feeling suppressed i nside their framework, which they would like to free. The opposition in the capital city of Kampala was again engaging, the fervor can be compared to the much-discussed overall show, â€Å"American Idol.† Through their support in that opposition, they were out to demonstrate that they can be mammoths in the midst of the enduring in their reality. The estimation of the move anyway in this film and the thumps of the drums, set some restriction concerning the messages that are should have been said in broad daylight, which now and again, no one but words can do. Inwardly, in an individual setting for the kids, they had the option to imagine that everything can be okay, yet when all is said in done, the desire for help and call for salvage are very subtle.

Health Issues Caused By PTSD

Health Issues Caused By PTSD PTSD Related Conditions Print How PTSD Relates to Physical Health Issues By Matthew Tull, PhD twitter Matthew Tull, PhD is a professor of psychology at the University of Toledo, specializing in post-traumatic stress disorder. Learn about our editorial policy Matthew Tull, PhD Medically reviewed by Medically reviewed by Daniel B. Block, MD on January 23, 2020 twitter linkedin Daniel B. Block, MD, is an award-winning, board-certified psychiatrist who operates a private practice in Pennsylvania. Learn about our Medical Review Board Daniel B. Block, MD on January 23, 2020 Post-Traumatic Stress Disorder Overview Symptoms & Diagnosis Causes & Risk Factors Treatment Living With In Children milan2099 / Getty Images People with post-traumatic stress disorder (PTSD) often experience a number of psychological difficulties such as depression, other anxiety disorders, and substance use-related problems;?? however, in addition to these psychological difficulties, individuals with PTSD may also be more likely to experience physical health problems.?? PTSD and Physical Health Problems Studies have found that compared to those without PTSD, people with PTSD are more likely to experience a number of physical health problems including for example:?? ArthritisHeart-related problems and diseaseRespiratory system-related problems and diseaseDigestive problems and diseaseReproductive system-related problemsDiabetesPain Given the number of physical health problems found to be associated with PTSD, it is not surprising that people with PTSD have been found to use and seek health care more than people without PTSD. How PTSD and Physical Health Issues Are Related Studies have found that there is something unique to PTSD (as opposed to simply being exposed to a traumatic event) that puts people at risk for developing physical health problems,?? and a number of theories have been proposed to explain this connection. It has been suggested that a variety of factors interact to increase the risk for physical health problems among people with PTSD. PTSD puts tremendous physical and emotional strain on a person. For example, as mentioned previously, people with PTSD tend to experience a variety of stressful psychological difficulties such as depression and other anxiety disorders.?? In addition, people with PTSD may engage in more risky and health-compromising behaviors, such as alcohol and drug use.?? The hyperarousal symptoms of PTSD may also put someone in a constant state of stress and anxiety. All of these factors may then combine to put tremendous strain and stress on a persons body,?? increasing the risk for physical health problems and illness. How to Improve Your Health If You Have PTSD If you have PTSD, your physical health may be at risk. Thats why it is important to seek out treatment for PTSD. The Anxiety Disorder Association of America provides a list of therapists across the United States who specialize in the treatment of PTSD. By speaking with a mental health professional, you are already making progress in coping with your PTSD. PTSD Discussion Guide Get our printable guide to help you ask the right questions at your next doctors appointment. Download PDF By reducing the psychological difficulties associated with PTSD, you may also reduce your risk of a number of physical health problems. As part of your treatment for PTSD, it may also be important to start focusing on living a healthier lifestyle. A healthy diet, exercise, and eliminating bad habits (for example, stopping smoking) may not only improve your health  but also your mood. Behavioral activation is one technique that provides an easy way to increase the level of activity in your life, help you meet your goals, and can reduce PTSD symptoms.?? PTSD: Symptoms and Diagnosis

Memoir of a Bilingual Childhood - Free Essay Example

Aria Memoir of a Bilingual Childhood by Richard Rodriguez is a personal essay. Originally published by the American Scholar Magazine belongs to an elite class of thought-leader magazine it is a literacy magazine made for the Phi Beta Kappa society(CLR, 236). This personal essay is directed to people who have gone through the same thing as Rodriguez. People who have their struggles with learning a new language too can relate to some of the things he says throughout his essay. Rodriguez takes reader back in his life about 30 years to when he moved and started school. Rodriguez was born and raised in a spanish speaking family that moved to California, Sacramento. Rodriguez shows throughout his essay, that you can conquer anything that comes in life even the hardest things like learning a completely new language. Rodriguez, during this essay, talks about when he was a child and the troubles he had with Spanish vs English. Rodriguez shows readers the struggle he had to go through as a child to understand English. English was his public language and spanish was his private language he spoke around his family. Since he didnt know a lot of english his home was his safe place he could escape from the real world there. Rodriguez would slowly start to learn the English language it was struggle at first. Later on that it flips english becomes his safe space once he gets out there and develops a public identity. While Rodriguezs experiences as a child made him uncomfortable, I have to agree with his claim that developing a public identity requires speaking the public language in this case english. While Rodriguezs argument is important the ease in which he dismisses his familys closeness undermines his argument. Rodriguez uses his personal experience to support his argument that learning the public language helped him to develop a public identity. Before his schooling he and his family would only use the public language (English) when going to the market/store or going somewhere else to get essentials but other than that the family stayed strictly to their main language, Spanish. Towards the end he explains that he experiences little snippets that reminded him of his past because the strangers he overheard were speaking their private language, and he felt confused to what they were saying. He says, These instances of hearing a Spanish voice made him flashback to the golden age of his childhood. This shows us that being a part of bilingual education can really shut off ones diverse individuality and the connection between a child and his/her culture that they have grown up and became accustomed to throughout their life. Rodriguez then goes off to explain the thoughts of a bilingualists, and it says, In a sense, he thought that it didnt do as much good as everyone thought it would because his life changed in a more unexpected way then he wanted it to. That bond that an individual has with their heritage and culture makes them feel unique in their own way and makes them feel like they know their place in the world. Rodriguez uses his time at school to show readers how he grew as a person from not speaking any English to fully grasping the English language in order to support his argument against bilingual education. From the early stages of schooling to the end of it, the change of meaning between the public and private languages and how the roles of them changed. After the nuns went to his house they asked his family to start speaking English as well, and from there the American mainstream became more relevant to Rodriguezs lifestyle.   The way Rodriguez quickly discards his familys intimacy in favor of a public identity may cause readers to question his judgement. He says, which helps us understand what his life was like before the nuns came over. Now just picture a kid who had a great life and who was culturally sound with his family, but after moving into a new life that new life being english and that close family became driven apart. This is identical to what this boy had to experience at a young age and he himself saw his own family getting broken apart as he grew up because they couldnt find the cultural identification of their relationship. That cultural bond that they had was crucial, and he even says, . He describes that he saw in his parents, and the discomfort that they were living with on a daily basis. It wasnt only his parents but his sisters and brother who were constantly getting frustrated because the intimacy at home was changing. After the Rodriguez family started to speak English and the children grew more fluent. He describes an instance at home where frustration got the upper hand, Its difficult to even read through these tough times because the reader can just visualize the changes that the family had to go through. His father became significantly quiet as time went on and he mentions, He not only noticed this muted behavior at home but when his father was out with other men. He noticed, and when he would speak Spanish, he felt like he had confidence and authority, but he continued to be quiet. As children grow up, they create a close bond with their parents and when that bond is broken then they feel helpless and confused, and this is how he felt just going on with daily life not knowing what was going to happen next because his parents could never keep up with him and the language. Rodriguez attitude stands in contradiction to the commonly held belief of family first, which might make readers question if Rodriguezs priorities are similar to their own. If they are different, then his priorities about education might also be different, leading us to question his judgement about the value of bilingual education. The carefulness with which Rodriguez describes his language use as a child gives a clear picture of how his understanding of language changed as he learned English. Rodriguez catches the readers attention by describing how life changed when English came into the picture. He explains that his parents spoke with and how He and his family described the Americans as gringos and they use it in a context that seems like theyre dealing with some alien that they cant understand but is merely just an American speaking another language than theirs. The phrase gringos is used less and less as he moves on because of the transition when his life becomes the American mainstream. All in all While Rodriguezs experiences as a child made him uncomfortable, I have to agree with his claim that developing a public identity requires speaking the public language in this case english. While Rodriguezs argument is important the ease in which he dismisses his familys closeness undermines his argument. Throughout the story Rodriguez shows the several hardships he has to endure to finally get his public identity. Conclusion All the way from walking in on the first day of class, that is where it all started just with one single step. As the story goes on you see that Rodriguez starts to grow as a person and starts to understand the english language step by step. Still has his bumps in the road but has his family to back him up still since he hasnt totally shut them out yet. In the end, you finally see Rodriguez blosum into this human that started with only knowing about fifty words and someone that only knew the spanish language. To someone who has a great grasp of the english language uses it all the time now and doesnt talk a whole lot of spanish anymore. The only problem with that though is Rodriguez starts to shut out his family and absolutely dismisses them. Rodriguez did finally find his public identity, which he needed to speak the his public language, English.